Famous People with Klinefelter Syndrome

Learn From Doctor Team
Learn From Doctor Team is made up of well-qualified doctors of different fields with brilliant academic results and professional careers. The article is written and reviewed by doctors of this specialty.


Some famous people with Klinefelter syndrome are working successfully in their profession, encouraging others with Klinefelter syndrome to be confident in their life. 

Klinefelter syndrome causes less testosterone production, resulting in less facial and body hair, broader hips, wide-spread breasts, weaker bones, etc. 

People with Klinefelter syndrome often become frustrated and depressed. Consequently, their grade falls, and they quit their jobs and desocialize themselves. 

On the other hand, some people are working great in their profession despite having Klinefelter syndrome. 

Famous people with Klinefelter syndrome motivate others and help them to be confident.


Top Famous People with Klinefelter Syndrome

George Washington

George Washington Klinefelter Syndrome
George Washington Klinefelter Syndrome

Although it is not proven, some historian believes that George Washington had Klinefelter syndrome. 

No introduction is needed for George Washington. He was the first president of the United States. 

He didn’t have any children, which indicates infertility, while his body features often indicate Klinefelter syndrome. 

Some historians suggest he has two children, both of whom are adopted, and that evidence supports that he had Klinefelter syndrome.

George Washington is the founding father of the United States. His devotion to this country is unforgettable. 

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Caroline Cossey

Caroline Cossey Klinefelter Syndrome
Caroline Cossey Klinefelter Syndrome

Caroline Cossey is a British model born in 1954 and known by the stage name “TULA.” She is well known for her appearance in the James bond film “For Your Eyes Only.” 

She was grown up as a male and always felt like a woman and confused about her sexuality. At the age of 17, she was diagnosed with Klinefelter syndrome. 

She started hormone therapy and always wanted to be a female. In 1974 she underwent sex reassignment surgery. 

When she wasn’t diagnosed, her classmates bullied her for her feminine look despite being a male. 

Caroline Cossey worked hard throughout her life. Before the surgery, she worked as a dancer in her early life. James bond’s film helped her reach the peak of her career.  

Caroline Cossey is a living inspiration for people with Klinefelter syndrome. 

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Caster Semenya

Caster Semenya Klinefelter Syndrome
Caster Semenya Klinefelter Syndrome

Caster Semenya is a South American athlete and gold medalist. He is believed to have Klinefelter syndrome, especially because he looks like a female. 

He has no facial hair and a womanly face; he just looks like a female. He had to undergo many gender tests and was banned from international events for about a year. 

His gender test results have never been public, so there is no proof of his Klinefelter syndrome. 

Despite having Klinefelter syndrome, he is an amazing athlete and a gold medalist, which inspires many people with Klinefelter syndrome. 

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Janet Mock

Janet Mock Klinefelter Syndrome
Janet Mock Klinefelter Syndrome

Janet Mock is an American writer and TV producer. He was born as a male and then underwent sex reassignment surgery and became a female. 

Her male name was Charles. 

She is suspected of having Klinefelter syndrome, but there is no absolute proof. She never replied to any questions about her sexualities order this condition. 

She’s working fantastically as a writer and TV producer. 

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Lauren Foster

Lauren Foster Klinefelter Syndrome
Lauren Foster Klinefelter Syndrome

Lauren Foster is a South African model who was born as a male later underwent surgery, and transformed into a female. 

In her early childhood, she diagnosed to have Klinefelter syndrome. She changed her sex organs and tried to identify herself as a female.

She wanted to participate in a beauty contest, but she got rejected. 

She’s working as a model in South Africa and is very successful. 

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Veronique Francoise Caroline Renard

Veronique Francoise Caroline Renard Klinefelter Syndrome
Veronique Francoise Caroline Renard Klinefelter Syndrome

Veronique Francoise Caroline Renard is a popular Dutch actress, author, and visual artist. She was born in 1965 in the Netherlands. She was born as a male, and then in 1982, she underwent surgery and became female. 

She was diagnosed with Klinefelter syndrome at an early age. Also, she had all the features of Klinefelter syndrome, such as a feminine look, wider hips, and wide-spaced nipples. 

Despite having Klinefelter syndrome and early surgery, she is a successful actress and author. Currently, she’s living in Singapore. 


Famous People With Unproven Klinefelter Syndrome

Tom Cruise

Tom Cruise Klinefelter Syndrome
Tom Cruise Klinefelter Syndrome

Who doesn’t know Tom Cruise? He is the most famous Hollywood star and was born in 1962. He is suspected of having Klinefelter syndrome. 

People believe he has a feminine face, low facial hair, and other body features associated with Klinefelter syndrome. 

He is married and has three children. There is no such data that proves he has Klinefelter syndrome. 

The most popular film series of Tom cruise is “Mission Impossible.” 


Lili Elbe

Lili Elbe Klinefelter Syndrome
Lili Elbe Klinefelter Syndrome

Lili Elbe is a Danish artist who was born in 1982. He underwent sexual resentment surgery in mid 20th century. He is well known for his feminine look and body features. 

He was suspected of having Klinefelter syndrome. However, no data proves that he had Klinefelter syndrome. 

He died at the age of 49 during the surgery that was performed to place a uterus inside him. 

He didn’t have any children. 


Jaime Lee Curtis 

Jaime Lee Curtis Klinefelter Syndrome
Jaime Lee Curtis Klinefelter Syndrome

Jaime Lee Curtis is a Hollywood artist born with a mixed sexual appearance. It is believed that she underwent sexual reassignment surgery to become a complete female. 

It is believed that she had Klinefelter syndrome, but no data supports that. She denied every question regarding her sexuality or sexual orientation. 

The gossip flares up because of her feminine look and her father giving her a common name that can be used for both males and females. 


What is Klinefelter Syndrome

Jennifer Richardson drone is a congenital condition where the person is born with an extra copy of the X chromosome. 

Normal people have either XX or XY chromosomes. On the other hand, a person with Klinefelter syndrome has XXY chromosomes. 

That extra X chromosome brings some feminine features despite the person being male. 

Klinefelter syndrome is not diagnosed during pregnancy. It can be diagnosed when the person is having trouble or wants to have children. 


What causes Klinefelter Syndrome

There is not enough data that can refer to the specific cause of Klinefelter syndrome. Some pregnancy risk factors can be associated with it. 

It causes when the sperm and female ovum comes together to form the zygote. 


Genetic Variation of Klinefelter Syndrome

The variations of Klinefelter syndrome may include;

  • A copy of the extra X chromosome in each cell; the most common variant
  • Some cells contain extra X chromosomes, while others are normal. It’s called the mosaic type. 
  • Cells may contain more than one X chromosome. It’s very rare and severe. 


Klinefelter Syndrome Symptoms

The symptoms of Klinefelter syndrome mostly occur after puberty. In some people, it occurs very late and is often diagnosed during the evaluation of infertility. 

The symptoms of Klinefelter syndrome vary from age to age. 

In Babies

  • Hernias may occur
  • Slower in daily activities such as crawling, standing
  • Babies are often quieter than other babies of the same age group
  • Weak muscle power
  • Testicles may not be dropped into the scrotum


In Children

  • Children are weaker than others
  • Poor learning capacities
  • Shyness
  • Hard to determine gender by the facial look


In Teenagers

  • Lack of facial hair
  • Larger breasts and nipples than normal
  • Less muscle tone
  • Longer arms and legs
  • Wider hips and a shorter torso
  • Small penis and small testicles
  • Puberty comes late or never comes
  • Taller than other family members


In Adult

  • Infertility
  • Low sexual drive
  • Low testosterone
  • Low libido
  • Erectile dysfunction



The best time to start treatment for Klinefelter syndrome is at puberty. The most common treatment of Klinefelter syndrome is known as Testosterone replacement therapy. 

When it started at puberty, testosterone would result in normal puberty changes such as growing facial hair, a manly voice, and body shape. 

Testosterone also plays a role in increasing the size of the penis. 

Some advice and counseling are a necessary part of Klinefelter syndrome treatment, which may include;

  • Klinefelter syndrome treatment can be started at any age, but the best outcome is achieved when the treatment is started at puberty.
  • Fertility treatment is needed.
  • Cosmetic surgery may be needed to reduce breast size.
  • Mental support may be needed.



Most of the complications of Klinefelter syndrome occurs due to lower testosterone level in the body. Common complications may include;

  • Autoimmune diseases such as systemic lupus erythematosus, Rheumatoid arthritis may arise
  • Breast cancers
  • Diabetes mellitus and other hormone-related conditions
  • Heart disease
  • Lung disease
  • Mental conditions due to social trauma
  • Osteoporosis and other bone conditions


Life with Klinefelter Syndrome

Life with Klinefelter syndrome is not easy as it seems. It shows signs and symptoms during puberty. A teenager’s mindset is not that strong to stay stable while his friends are making fun of him. 

A large number of people with Klinefelter syndrome are also fighting depression. 

Treatment is needed for a long time, and a couple’s infertility leads to relationship problems. 

People with Klinefelter syndrome need support. However, some famous people with Klinefelter syndrome are doing great in their professions. They are inspiring others. 



Klinefelter syndrome is a genetic condition in which there is an extra copy of the “X” chromosome in the cell. The most common genotype of Klinefelter syndrome is “XXY.” 

Famous people with Klinefelter syndrome motivate others to stay strong and fight back against the conditions. 

People with Klinefelter syndrome often get criticized by other people, which should be stopped. 


Last Updated on December 17, 2022 by Learn From Doctor Team

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